I-Tolvaptan CAS 150683-30-0 API Factory High Quality

Incazelo emfushane:

Igama Lekhemikhali: Tolvaptan

I-CAS: 150683-30-0

I-Assay (HPLC): 98.0~102.0%

Ukubukeka: I-Crystalline Powder Emhlophe ukuya Kokumhlophe

Umphikisi onamandla futhi okhethiwe we-vasopressin V2 receptor

Ikhwalithi ephezulu ye-API, Ukukhiqizwa Kwezohwebo

Umbuzo: alvin@ruifuchem.com


Imininingwane Yomkhiqizo

Imikhiqizo Ehlobene

Omaka bomkhiqizo

Incazelo:

Ukuhlinzekwa komkhiqizi
Ikhwalithi Ephezulu, Ukukhiqizwa Kwezohwebo
Igama Lekhemikhali: Tolvaptan
I-CAS: 150683-30-0

Chemical Properties:

Igama I-Tolvaptan
Igama Lekhemikhali N- [4-(9-chloro-6-hydroxy-2-azabicyclo[5.4.0]undeca-8,10,12-triene-2-carbonyl)-3-methyl-phenyl]-2-methyl-benzamide
Inombolo ye-CAS 150683-30-0
Inombolo yeCAT I-RF-API101
Isimo Sesitoko Esitokweni, Isikali Sokukhiqiza Sifinyelela Kumathani
I-Molecular Formula I-C26H25ClN2O3
Isisindo samangqamuzana 448.94
Ibhrendi I-Ruifu Chemical

Imininingwane:

Into Imininingwane
Ukubukeka I-Crystalline Powder emhlophe ukuya kokumhlophe
Izindlela Zokuhlonza IR, HPLC
I-Assay (HPLC) 98.0 ~ 102.0% (kusisekelo se-anhydrous)
I-Melting Point 219.0~222.0℃
Ukulahlekelwa Ekumisweni ≤0.50%
Izinsalela Ekushiseni ≤0.10%
Ukungcola Okukodwa ≤0.50%
Ukungcola Okuphelele ≤1.0%
Izinsimbi Ezisindayo ≤20ppm
Izincibilikisi Ezisele Hlangana nencazelo
Izinga Lokuhlola I-Enterprise Standard
Ukusetshenziswa Pharmaceutical Intermediates

Iphakheji nesitoreji:

Iphakheji: Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwezidingo zekhasimende.

Isimo Sesitoreji:Gcina ezitsheni ezivaliwe endaweni epholile neyomile;Vikela ekukhanyeni nakumswakama.

Izinzuzo:

1

I-FAQ:

Isicelo:

I-Tolvaptan (i-CAS 150683-30-0), eyaziwa nangokuthi i-OPC-41061, iyisitha esikhethiwe, esincintisana ne-arginine vasopressin receptor 2 esetshenziselwa ukwelapha i-hyponatremia (amazinga aphansi e-sodium yegazi) ahlotshaniswa nokuhluleka kwenhliziyo, i-cirrhosis, nesifo sokungafaneleki. i-antidiuretic hormone (SIADH).I-Otsuka Pharmaceutical enelayisensi ye-tolvaptan ngaphansi kwegama lokuhweba i-Samsca ngemuva kokuthi i-FDA igunyaze umuthi ngoMeyi 2009. I-Tolvaptan iphinde yabonisa ukusebenza kahle ngokumelene nesifo sezinso se-polycystic.Ocwaningweni lwango-2004, i-tolvaptan esetshenziswa nge-diuretics yendabuko yaphawuleka ukuthi inyusa ukuphuma koketshezi oluningi futhi ithuthukise amazinga e-sodium egazini ezigulini ezinokwehluleka kwenhliziyo ngaphandle kokukhiqiza imiphumela emibi efana ne-hypotension (umfutho wegazi ophansi) noma i-hypokalemia (ukwehla kwamazinga e-potassium egazini).Umuthi futhi awuzange ubonise umthelela omubi ekusebenzeni kwezinso.

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